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The elevated GPx in extracellular fluids may reflect release from inflammatory/damaged cells or a compensatory response compromised by GSH scarcity (Dauletbaev et al., 2004)

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Important early changes occur before severe cell damage take place but no universal markers have yet been identified 21

PTX treatment reversed this inhibition, suggesting that insulin secretion is inhibited by pasireotide via SSTRs-Gi-dependent cAMP inhibition (Fig

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