Patients in the HGSH group exhibited significantly higher recurrence rates, and mortality compared to the LGSH group
However, while there is a stronger stimulation of insulin secretion in response to GEP12 vs
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In the SUSTAIN clinical trials, average weight loss with Ozempic 0.5 mg was approximately 34 kg, and with 1 mg approximately 46 kg over 612 months, though individual responses vary considerably
While real-world results may be slightly less, the improvements go beyond weight: Lower blood sugar, blood pressure, and triglycerides Reduced waist circumference and sleep apnea symptoms Better health-related quality of life Fewer major cardiovascular events Reduced progression of fatty liver disease and chronic kidney diseaseeven in the absence of weight loss (Mozaffarian et al., 2025)