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Equillium (NASDAQ: EQ) shares plummeted 38% from $1.38 to 86 cents Thursday after the company said collaboration partner Ono Pharmaceutical let lapse its option to acquire Equilliums rights to itolizumab, a monoclonal antibody targeting the CD6-ALCAM signaling pathway, which plays a key role in modulating effector T cells that drive numerous immuno-inflammatory diseases

Despite some GLP-1 drugs being used for conditions other than obesity and weight loss, authorization is still required

Transgenerational effects of prenatal exposure to the Dutch famine on neonatal adiposity and health in later life

doi:10.1016/j.bbr.2009.07.020, PMID: 19643148 Kumar A, Garg R (2009) Protective effects of antidepressants against chronic fatigue syndrome-induced behavioral changes and biochemical alterations

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GLP-1 medications create the caloric deficit by suppressing appetite and slowing gastric emptying