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8.7 Hepatic Impairment In patients with mild (Child-Pugh 5 to 6) and moderate (Child-Pugh 7 to 9) hepatic impairment, exposure to phentermine was higher compared to healthy volunteers with normal hepatic function

Patel R, Sushko K, van den Anker J, Samiee-Zafarghandy S

For the tube formation assay, 50 L of Matrigel (Corning, Glendale, AZ, USA) was loaded into each well of a 96-well plate, and the plate was incubated at 37C for 30 min before culture

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This characteristic could be linked to the increased incidence of POI after chemotherapy 118