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The photothermal effect of HEA Different concentrations of GHEA cell solution (1 mL) were exposed to a 658 nm laser (0.5 W/cm 2 ) for 10 min

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Disrupted peripheral neurogenic signaling pathways between the liver and the brain axis, coupled with perturbed central neurotransmission within the brain, in tandem with disease-related or disease-associated factors, such as complications, treatments, and severity, as well as alcohol use, metabolic syndrome, and malignancy, collectively contribute toward clinical fatigue ( 2.3 Diagnosis and management Peripheral fatigue can be quantified through objective assessments of strength and aerobic capacity, while central fatigue is evaluated using self-reports and validated questionnaires that capture the patients perception of physical and mental exertion impacts on their activities and exertion levels