Anaphylaxis following a B12 injection has been documented in medical literature, particularly in patients with a sensitivity to cobalt or cobalamin compounds
In this article, we'll walk you through the proper injection process so you can easily give yourself (or someone else) a painless B12 shot
common reactions include transient pain, erythema, or pruritus at the administration site, along with mild diarrhea, headache, or nausea in a minority of recipients
Intramuscular injections of B12 are administered during the first stage of the test, an hour after the patient takes an oral dose of radiolabeled vitamin B12
intracellular half-life is prolonged because of lysosomal release and cytosolic resequestration, creating a depot effect that supports monthly maintenance dosing for chronic deficiencies
PMID: 33980297