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Dual GIP/GLP-1 receptor agonists Sometimes called dual agonists or twincretins, as they activate the GLP-1 receptor plus a second receptor, called GIP (glucose-dependent insulinotropic polypeptide)

Woronow D, Chamberlain C, Niak A, Avigan M, Houstoun M, Kortepeter C

The primary endpoint, major adverse cardiovascular events (MACE), was the time to first occurrence of a three-part composite outcome which included CV death, non-fatal myocardial infarction (MI) and non-fatal stroke

There is no regulator-approved time-course expectation

It is also able to promote the production of pulmonary surfactant through its phospholipid repair activity

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