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To achieve optimal model performance, Bayesian Optimization was used for hyperparameter tuning, and a rigorous cross-validation strategy ensured reliable evaluation

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GC samples Patient-derived tumor fragments (3-4mm 3 ) were surgically xenografted under the skin of 6-week-old male NCG mice

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Stabilization stack we commonly apply: liposomal shielding / nitrogen-protected manufacturing windows / synergistic antioxidant co-formulation / low-temperature emulsification and blending Layer 4 Functional Synergy & Metabolic Support Design To strengthen antioxidant-network positioning (claim-safe), formulas may integrate: Endogenous glutathione recycling support (e.g., ascorbate systems) Redox-balance companions that support GSH/GSSG narrative without medical claims Enzymatic cofactor support (e.g., selenium-dependent pathways, where market-allowed) Complementary antioxidant network ingredients (ALA, polyphenols, CoQ10-format-dependent) Synergy is selected for lipid/aqueous compatibility and regulatory fit , not ingredient-count marketing

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