In confluent cell monolayers, including epithelial models such as MCF10A mammary epithelial cells, ferroptotic death can propagate in wave-like spatiotemporal fronts through neighboring cells
Therefore, preventing the buildup of lipid peroxides appears to be a promising approach for addressing ferroptosis
For example, certain types of peptide linkers are designed to be cleaved by enzymes abundant in tumor cells to selectively release drugs to these cells
The incidence of hyperthyroidism in Austria from 1987 to 1995 before and after an increase in salt iodization in 1990
Effects of diabetes on microglial physiology: a systematic review of in vitro, preclinical and clinical studies
Additionally, peptides such as BPC-157 support gut health and digestive repair by strengthening gut lining integrity, reducing inflammation, and promoting healing in conditions like leaky gut syndrome