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The compound is not FDA-approved for any systemic indication

TSA allows frozen gel packs and cooling cases through airport security when packed with medication, making international travel feasible for ongoing GLP-1 therapy

The Bottom Line Wellbutrins weight-loss side effect is real, moderate, and usually safe

It is made by your body and is also available as a supplement

The transition from diabetes-only to weight-loss indication happened gradually through clinical evidence and media attention

The compounded preparation you receive from Trimi is made per your individual prescription by a licensed 503A pharmacy and is not itself FDA-approved as a drug