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[14] Review literature reports that endogenous plasma GHK falls from roughly 200 ng/mL around age 20 to under 80 ng/mL by age 60
Their role in specific areas, such as fat metabolism and weight loss, remains unclear and is not substantiated by significant clinical evidence
This binding cooperativity results from the molecule's ability to also mimic the homodimeric structure of Smac, which is functionally important for reactivating caspases
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This gap should be openly acknowledged: GHK-Cu is a promising therapy, but not yet an established standard
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