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While the root causes of Hashimotos will still need to be addressed, even with the use of metformin, this sounds promising right
sitagliptin Sitagliptin Trade Name: Januvia Drug Class: oral hypoglycemics Mechanism of Action: An inhibitor of dipeptidyl peptidase-4 (DPP-4), a protease that degrades the incretin GLP-1 Incretins are hormones released from the GI tract in response to nutrient ingestion Incretins potentiate glucose-stimulated insulin secretion from beta cells in the pancreas As a result of inhibiting DPP-4, increased or prolonged GLP-1 levels are able to potentiate the secretion of insulin by the pancreas The effect produced by DPP-4 inhibitors is dependent on endogenous GLP-1 levels, and produce a modest effect on GLP-1 activity compared to giving GLP-1 receptor agonists (hence DPP-4 inhibitors do not have the same impact to produce weight loss as GLP-1 agonists)
Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10
Meyer R (2003)
Tirzepatide and similar medicines work like these hormones
The difference between 7 and 8 units at this concentration is only about 0.033 mg, a negligible variance
