In addition, tirzepatide affects certain chemicals in the brain which in turn decreases appetite, increases energy expenditure, and prevents ectopic fat deposition (abnormal fat accumulation in body parts that normally contains small amounts of fat)
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2), a2853 (2013)
These include furosemide, thiazide diuretics, and ritodrine, as GLP-1 usage can decrease their effectiveness, primarily due to delayed absorption.7 Semaglutide medications may also impact thyroid function by increasing serum levothyroxine.7 All GLP-1 medications are a known risk factor for acute pancreatitis.16 While research is limited, there is concern that GLP-1s may contribute to the onset, maintenance, or worsening of disordered eating behaviors
Cellular and Molecular Neurobiology