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PMID: 28243487 van der Merwe J, Brooks NE, Myburgh KH

It has been shown that in white blood cells of HD patients some biomarkers of oxidative damage to DNA [8-hydroxy-2 -deoxyguanosine content of leukocytes (8-OH-dG), and DNA strand breakage (alkaline comet assay)] are higher than in healthy controls

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But even that is rare

But, before frustration sparks at yet another suggestion of more sleep, consider this according to NHS UK, extreme tiredness, a lack of energy, and problems with your memory, understanding and judgement could be signs that you are lacking in Vitamin B12