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Long-term effects of calorie or protein restriction on serum IGF-1 and IGFBP-3 concentrations in humans

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While some individuals may notice initial changes in appetite and a small amount of weight loss within the first few weeks, significant and sustained weight loss generally unfolds over several months

Within the tirzepatide treatment arm, the studys most common adverse effect, gastrointestinal disorders, occurred in 46.0% of patients who experienced a cardiorenal end point versus 41.4% of patients who did not

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