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Did you know that individuals using semaglutide experience average weight reductions ranging from 9.6% to 17.4% of their initial body weight

Led by Lorenzo Leggio, MD, PhD of The National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the research outlines how activation of GLP-1 receptors in the brain may modulate reward circuits involved in substance craving and dependence

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Low protein intake on GLP-1 medications causes muscle loss, which worsens fatigue

For these patients, escalating to 2.4 mg adds side-effect risk without meaningful benefit