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Frozen cortical samples were homogenized in 50 mM TrisHCl (pH 7.5), 150 mM NaCl containing 1% Triton X-100, protease inhibitor cocktail and phosphatase inhibitor cocktail

[Abstract] Mol Brain

IGF-1 is the main mediator of many of growth hormones effects, very its anabolic effects on muscle and bone

Resistance mechanisms are multifaceted, often involving genetic mutations, epigenetic alterations, or modifications in signaling pathways that protect cancer cells from cytotoxic agents

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