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Granata A, Maccarrone R, Anzaldi M, Leonardi G, Pesce F, Amico F, et al (2022) GLP-1 receptor agonists and renal outcomes in patients with diabetes mellitus type 2 and diabetic kidney disease: State of the art

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Studies using doubly labeled water show that resting energy expenditure drops by 50 to 100 calories per day within 8 to 12 weeks of starting an SGLT2 inhibitor, partially offsetting the urinary glucose loss (Ferrannini et al., Diabetes Care 2014)

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66 SOD1 is constitutively expressed and it is abundant in bronchial and alveolar epithelial cells, fibroblasts, and capillary endothelial cells