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How Wegovy Affects Appetite and Food Preferences Wegovy works by mimicking the action of GLP-1, a naturally occurring hormone released by the intestine after eating

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Trulicity activates the GLP-1 receptor, helping your body lower blood glucose by increasing insulin release when blood sugar is high, reducing how much glucose the liver produces, slowing stomach emptying, and helping you feel fuller sooner

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These states also require prescribers to document failed trials with FDA-approved alternatives before prescribing compounded peptides