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In a separate survey by Omada Health in partnership with Sermo, more than two-thirds (67%) of primary care physicians expressed concern about patients accessing GLP-1 prescriptions for weight loss through a third-party telehealth provider, saying it may put their patients' health at risk

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Previous studies in mice have reported that matched, unbiased agonists are less effective at controlling glucose and body weight than GLP-1RAs with bias similar to that of tirzepatide [35, 36]

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For people with a history of severe gastrointestinal disorders, caution is advised when considering GLP-1 receptor agonists

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