GH activates Janus kinase 2 (JAK2)/STAT and Src/MAPK pathways after binding to GH receptor (Woelfle et al., 2003)
Furthermore, oxidative stress influences immune pathways in vitiligo by promoting the release of melanocyte autoantigens that are detected by local dendritic cells
View at Publisher | View at Google Scholar Daenen K, Andries A, Mekahli D, Van Schepdael A, et al
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Several mechanisms have been proposed, including inhibition of free fatty acid release from adipose tissue, increased lipoprotein lipase activity, decreased triglyceride synthesis, decreased VLDL-triglyceride transport, and an inhibition of lipolysis
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