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The 4.0mL option is rarely used because it creates impractically large injection volumes at 8mg and above
bioRxiv2025 Sep 25
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After a single hydroxocobalamin injection, therapeutic levels can be maintained for approximately 8 to 12 weeks in most patients, which aligns with the standard maintenance schedule of injections every 2-3 months recommended in the British National Formulary (BNF)
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