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1039 Development of a tree-based graded response model R package to test for differential item functioning in patient-reported outcome measures Olayinka Arimoro 1 , Matthew James 1 , Maria Santana 1 , Lisa Lix 2 , Tolulope Sajobi 1 1 University of Calgary, Calgary, Alberta, Canada, 2 University of Manitoba, Winnipeg, Manitoba, Canada Journal of Patient-Reported Outcomes 2026 , 10(Suppl 1) :1039 Aims Tree-based item response theory (IRT) models are a class of novel methods for testing differential item functioning (DIF) in patient-reported outcome measures (PROMs)

Los investigadores realizaron un estudio de cohorte retrospectivo para comparar el riesgo de depresin incidente en adultos con T2D que iniciaron una de las cuatro clases diferentes de medicamentos para reducir la glucosa (GLP-1 RA, inhibidores de SGLT2, inhibidores de DPP4 y SU)

Muscle fiber necroptosis in pathophysiology of idiopathic inflammatory myopathies and its potential as target of novel treatment strategy