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Summing up, it seems that the role of the GLP-1 pathway in the regulation of neurotransmission in the central nervous system cannot be omitted when assessing the influence of this factor on changes observed in depression

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Individuals should consult a doctor if side effects persist or worsen

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Avoid using any lotion or cream in the same area as it will inhibit absorption

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While semaglutides primary function is not to directly target the nervous system, its ability to reduce inflammation could indirectly help calm these overactive pain pathways

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