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NICE guidelines recommend hydroxocobalamin 1 mg intramuscularly three times weekly for 2 weeks (without neurological involvement) or on alternate days until no further improvement (with neurological symptoms)
In younger individuals or those who lost weight gradually, the skin can sometimes remodel itself over 12 to 24 months
At 20 years, the average concentration of GHK-Cu of 200 ng/mL declines to 80 ng/mL by 60 years
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BMC Psychiatry 2018;18:279
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