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Most patients experience improvement in previously elevated liver enzymes as weight loss progresses, though persistent or progressive elevation warrants prompt evaluation for alternative causes

Front Nutr , 8 , 702802

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Others leverage the gut-brain axis and serotonin pathways to affect mood, hunger, and food cravings

Recent advances in understanding NRF2 as a druggable target: development of pro-electrophilic and non-covalent NRF2 activators to overcome systemic side effects of electrophilic drugs like dimethyl fumarate

Hence, we have opted for a bicycle ergometer test lasting 13 min for our study