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IGF-1 LR3 and Glucose Metabolism Research In differentiated 3T3-L1 adipocytes, IGF-1 LR3 was used to investigate IGFBP-independent IGF-1R-mediated glucose uptake pathways, with research confirming that its effects on glucose transport are mediated directly through the IGF-1 receptor rather than through IGFBP modulation providing a clean experimental tool for dissecting receptor-specific metabolic signalling
Cette molcule joue galement un rle dans le transport des acides gras dans les mitochondries
Reproductive outcomes, endocrine endpoints such as androgen levels and menstrual regularity, and patient-centered outcomes were not assessed
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