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This unified mechanism underpins the clinical efficacy observed across all FDA-approved GLP-1 RAs, though individual agents differ in pharmacokinetics and the relative emphasis on gastric versus central pathways

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108 Another retrospective study reported that in a population with T2DM and previously diagnosed MASLD/MASH, GLP-1RA is associated with a decreased incidence of hepatocellular carcinoma (HCC) and a reduced risk of hepatic decompensation events compared with other antidiabetic agents

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