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siRNA targeting LRP5 (GGACAGACUCAGAGAGACCAA) was transferred into the BMSCs with the help of Lipofectamine 3000 (Invitrogen, United States), and all operations were carried out under the manufacturers instructions

p-heterogeneity = 0.26), while the risk for composite kidney outcome did not vary by SGLT2i use

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Despite the severe impact on individuals and society, there are no approved treatment options