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Inflammatory Response They modulate inflammatory cytokine profiles in the reproductive tract, downregulating proinflammatory mediators like TNF-, IL-6, and IL-1, and sometimes increasing anti-inflammatory cytokines such as IL-10

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doi: 10.1007/s10517-006-0323-9

The change extends the proteins half-life and permits it to disrupt normal FOXO4 function

These findings have generated significant research interest in the compound as a tool for investigating HGF/c-Met-associated signaling networks, synaptic regulatory processes, and molecular pathways governing neuronal connectivity