A study comparing injections into the abdomen, thigh, and upper arm found that tirzepatide reaches the bloodstream at similar rates regardless of which site is usedone location doesnt work better than another
Perhaps more importantly, GIP receptor activation appears to reduce the nausea that GLP-1 agonists can cause, which helps explain why Tirzepatides tolerability surprised many researchers
The slowed gastric emptying can also mean that high-fat meals, including ice cream, sit in the stomach longer, potentially intensifying feelings of fullness or discomfort
Haqq AM, Chung WK, Dollfus H, Haws RM, Martos-Moreno G, Poitou C, et al
Acharya KD, Friedline RH, Ward DV, et al
Rodrigues et al