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This critical balance between survival and cell death is orchestrated by the coordinated activity of the three canonical UPR branches, IRE1, PERK, and ATF6, which together determine cell fate decisions under stress

High GPx3 expression was associated with reduced overall patient survival and increased tumor stage

Globally, B12 deficiency affects a significant portion of the population, ranging from 6% in some groups to as high as 20% in older adults

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"N-acetylcysteine reduces disease activity by blocking mTOR in T cells from SLE patients." Arthritis Rheum

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