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It is best taken in the morning after waking up, although it can be taken at any time

This is particularly beneficial for older adults and those at risk of cognitive decline

Mayo Foundation for Medical Education and Research

[32] del Greco M FD, Minelli C, Sheehan NA, Thompson JR

Though an elevated number of native LDL particles does not directly endanger endothelial cells, it does mean that there are more LDL particles available to become oxidized (or otherwise modified), which then become more likely to damage endothelial cells

While vitamin D toxicity usually happens with very high intakes of 10,000+ IU per day, experts suggest that even amounts less than the UL could have negative health effects