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Mental health concerns like depression and anxiety have been reported, though theres no definitive proof the drug causes them

In conclusion, this review indicates that the effects on HR differ within the class of GLP-1 RAs: short-acting GLP-1 RAs are associated with a modest and transient HR increase before returning to baseline levels, while some long-acting GLP-1 RAs are associated with a more pronounced and sustained increase during the day and night

The change of objective function value (OFV) was used as the covariate inclusion criteria

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