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This pattern was evident in the case report where pain developed when the dose increased from 7.5 mg to 10 mg

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10.1007/s12035-022-02934-z 30

Binding of GLP-1 to GLP1R has multiple effects, including enhancing insulin secretion from pancreatic beta cells in response to glucose, increasing insulin expression, preventing beta-cell apoptosis, promoting the formation of new beta cells, reducing glucagon secretion, slowing down stomach emptying, promoting satiety, and improving glucose disposal in peripheral tissues

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