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Combining in the syringe doesn't create new compounds or reduce efficacy
Expert Interview Muhammad Khan, MD, MPH
Semaglutide is designed for subcutaneous injection , meaning it belongs in the fatty layer just beneath the skin
Limitations of this approach, however, include the lack of quantitative analysis and of a structured assessment of the quality of studies and certainty of evidence, which were beyond the scope of this descriptive work
However, the risks associated with its use are non-trivial, particularly given the lack of regulatory approval and the potential for serious side effects