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Surgery becomes more reasonable when the mechanism is clear and non-surgical treatment is not enough
Tesofensine becomes valuable when the bigger issue is metabolic slowdown, fatigue, or plateauing after initial GLP-1 success
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Incorrect procedures compromise experimental results and introduce potential hazards
Quick FAQ Once a week, what day works best
NICE obesity guidance (CG189) recommends multicomponent interventions addressing diet, physical activity, and behaviour change as first-line management
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