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Supplementary Material Disclosure Forms (nejmcibr2501084_disclosures.pdf) Download 146.59 KB Information & Authors Information Published In New England Journal of Medicine Pages: 2065-2068 Copyright Copyright 2025 Massachusetts Medical Society

This discovery has led to a whole new category of treatment called hormone therapy

Similarly, right upper quadrant pain, fever, or jaundice could signal gallbladder disease, which occurs at higher rates in patients taking semaglutide

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In a controlled study cited in the same review, participants who slept 5.5 hours per night lost less fat and more fat-free mass than those who slept 8.5 hours per night. The authors reported that sleep curtailment decreased the proportion of weight lost as fat by 55% and increased the loss of fat-free body mass by 60%. Poor sleep has also been linked to increased hunger and changes in appetite-regulating hormones

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