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At 104 weeks, participants with a baseline body mass index (BMI) of at least 35 achieved an average weight loss of 30.3% (85 lbs)

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[62] [63] The mechanism of action is straightforward: the hydroxycobalamin hydroxide ligand is displaced by the toxic cyanide ion, and the resulting non-toxic cyanocobalamin is excreted in urine

This period can help prevent overlapping effects , especially gastrointestinal ones, while allowing your body to reset