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In cell culture studies, -tocopherol was found to improve the formation of an adhesive junction (known as immune synapse) between nave T lymphocytes and antigen presenting cells (APC), which eventually prompted T cell activation and proliferation (see Disease Prevention) (6, 7)

TosicMOttJBarralSBovetPDeppenPGheorghitaFet alSchizophrenia and oxidative stress: glutamate cysteine ligase modifier as a susceptibility gene

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It was found that male mice were protected from the depressogenic effects of centrally or peripherally administered lipopolysaccharide (LPS) when IDO activity was inhibited through pharmacological or genetic manipulation [113, 114]

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