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The translation of these findings requires cautious interpretation and further rigorous human studies to establish efficacy, safety, and optimal dosing

Is it Safe

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Yes, Semaglutide is FDA-approved for chronic weight management and has been used safely for many years in diabetes care

It is released by intestinal L-cells after a meal and, separately, by preproglucagon neurons in the nucleus tractus solitarius of the brainstem, which gives the peptide both a peripheral endocrine role and a central neural one