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I think the reason we are seeing these increased reports of side effects (150 cases of self harm or suicidal ideation in the EU, which is a small number) is simply because more people are taking them and because people are mistaking the secondary effects of weight loss with the side effects of the drug

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Alcohol can affect glycemic control, increase hypoglycemia risk (especially with insulin or sulfonylureas), and contribute to weight gain

Exactly why Metformin is the star subject of ongoing clinical trials on anti-aging (12, 13)

If you notice facial changes with GLP-1 medications, treatments like dermal fillers or biostimulators (such as Sculptra) can help restore lost volume