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Treatment of mutant lysates or supernatants with the reducing agent DTT (dithiothreitol) collapsed practically all the protein to monomeric size, suggesting that disulfide bonds, either intramolecular or intermolecular, are required for observation of multimers and larger species on denaturing sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE)
Improved cardiovascular hlth Individuals with growth hormone deficiency are at a greater risk of developing heart problems
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