These long half-lives are the result of fatty acid conjugation and albumin binding, which delay renal and enzymatic clearance
Belaya I, Ivanova M, Sorvari A, Ilicic M, Loppi S, Koivisto H, et al
PMID: 21896138
mTOR controls lysosome tubulation and antigen presentation in macrophages and dendritic cells
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To verify if the increased expression of GCLC , GSS , and GSR had a functional impact on the activity of the GSH pathway, we measured total intracellular glutathione levels and ratio of reduced (GSH) to oxidized (GSSG) glutathione after 24 hours of BDG exposure ( Figure 4D )