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While waist circumference reduction showed a modest association with cardiovascular benefit, it accounted for only 33% of semaglutide's treatment effect on major adverse cardiovascular events.[1] This suggests that the majority of cardiovascular benefit occurs through mechanisms beyond adiposity reductionincluding direct effects on inflammation, endothelial function, blood pressure, and lipid metabolism

Once ALC passes through the blood-brain barrier, it helps promote synthesization of a primary neurotransmitter in the brain known as acetylcholine, which primarily allows for communication between nerve cells

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Diabetes Res Clin Pract (2019) 157:107843

Small amounts of healthy fat (avocado, olive oil) rather than heavy/fried meals

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