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While these plants contain various phytochemicals, it is the potent and highly bioavailable compounds within the glucosinolate/myrosinase/ITC system that uniquely contribute to the highly potent indirect antioxidant properties of these vegetables
Using pharmacy receipt data anchored to initial GLP-1 prescriptions in 2021 from a large PBM, one early study revealed that only 32% GLP-1 patients remained on these weekly injections after 12 months and only 15% after two years.[16] This is an 85% two-year rejection rate not too far off from otherwise successful, consumer packaged goods brands Ive worked with
That's far less than the 15% to 21% body weight reduction promised by the clinical trials that led to the approval of Wegovy (semaglutide) and Zepbound (tirzepatide) for weight loss, researchers said
Novo has already asked regulators to expand Saxendas label to children as young as 6, contingent on the results of this trial, and the company is testing Wegovy, a stronger GLP-1, in that age group as well
Ozempic (aka semaglutide), is FDA approved for Type II diabetes and has multiple studies that show benefits for weight loss and improvement, particularly in patients with knee arthritis
Its elimination half-life is extraordinarily long (168 h), its potency is exceptionally high, its therapeutic window is wide, and its clinical effects are driven by time-integrated exposure rather than peak concentration
