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In the Phase 3 ATTAIN-1 trial, orforglipron 36 mg reduced weight by an average of 12.4% (27.3 lbs) compared to 0.9% with placebo at 72 weeks

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A 2026 report on Direct Meds' GLP-1 platform and LegitScript certification status provides additional context on the company's regulatory standing during a period of heightened industry scrutiny

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