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doi: 10.1017/S0007114517001039 118 FanZYangBRossRPStantonCZhaoJZhangHet al

To activate Cre recombinase and induce Gclc deletion in tumour pieces from Gclc f/f Rosa26 creERT2 MMTV-PYMT mice, female mice were intraperitoneally injected with tamoxifen (Sigma-Aldrich, T5648) at 50160 mg kg 1 once daily for 5 consecutive days

The practical challenge has always been that conventional retinol formulations can irritate the skin, potentially undermining the repair environment that copper peptides are trying to create

Mice were humanely euthanized before the tumor burden reached the maximum permitted size if they met any of the following predefined humane endpoint criteria: (1) tumor volume exceeding 1500 mm

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