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It binds to GLP-1 receptors in the body, which helps slow how quickly the stomach empties, supports a feeling of fullness after meals, and helps the pancreas release insulin at more appropriate times

Specific amino acid substitutions confer resistance to dipeptidyl peptidase-4, a primary clearance pathway for native GLP-1, while attachment of a C18 fatty acid side chain promotes strong, reversible binding to serum albumin

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In theory, more body fat should mean more leptin signaling, which should prevent overeating

SGLT2 inhibitors like Jardiance can cause diuresis, or fluid loss, which could lead to dehydration in an individual already urinating more often due to caffeine