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GLP-1 inhibits glucagon release by regulating -cell N- and L-type Ca2+ channel-dependent cytokinesis (De Marinis et al., 2010)
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Another trial showed NAC (600 mg 2 daily) increased cellular glutathione by 35% and reduced oxidative stress markers by 25% [9]
Defective autophagy heightens TECs susceptibility to ferroptosis in DKD, demonstrating the close correlation between autophagy flux impairment and ferroptosis (79)
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If the FDA ultimately moves toward broader acceptance, or even formal inclusion on the 503A bulks list, providers could see clearer pathways for incorporating these therapies into patient care plans
